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The micrOTOF is an electrospray ionization (ESI) instrument with a time-of-flight (TOF) detector. The TOF mass analyzer gives high mass accuracy (<5 ppm) and resolution (10,000) for confirmation of molecular formula and accurate protein/peptide fragment assignment. The micrOTOF is regularly used for evaluating recombinant proteins, providing accurate mass for novel organic synthesis products, quantitation of known metabolites, and for biophysical studies such as hydrogen-deuterium exchange of proteins.

Other Features

  • ESI source is a "gentle" ionization method which makes it possible to analyze extremely large molecules.
  • Delivers solvent flow rates between 10 microliters and 1000 microliters per minute